[HTML][HTML] Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth …
LC Giudice, NA Martina, RA Crystal, S Tazuke… - American journal of …, 1997 - Elsevier
OBJECTIVES: Preeclampsia is characterized by maternal hypertension, proteinuria, edema,
and shallow placental invasion. Insulin-like growth factor binding protein-1, abundant in
maternal decidua, is believed to play a role in limiting trophoblast invasiveness. In this study
we addressed the hypothesis that this binding protein is aberrantly expressed in
preeclampsia. We also investigated circulating levels of insulin-like growth factor-I and
insulin-like growth factor-II in subjects with severe preeclampsia compared with controls …
and shallow placental invasion. Insulin-like growth factor binding protein-1, abundant in
maternal decidua, is believed to play a role in limiting trophoblast invasiveness. In this study
we addressed the hypothesis that this binding protein is aberrantly expressed in
preeclampsia. We also investigated circulating levels of insulin-like growth factor-I and
insulin-like growth factor-II in subjects with severe preeclampsia compared with controls …
