Biochemical evidence of impaired trophoblastic invasion of decidual stroma in women destined to have preeclampsia
CJM de Groot, TJ O'Brien, RN Taylor - American journal of obstetrics and …, 1996 - Elsevier
OBJECTIVE: Reduced trophoblastic migration into the decidua during the first half of
pregnancy is a fundamental abnormality in preeclampsia. CA 125 and insulin-like growth
factor binding protein-1 are major endometrial proteins whose primary sources are decidual
epithelial and stromal cells, respectively. We hypothesized that reduced trophoblastic
invasion in pregnancies destined for preeclampsia would affect the maternal vascular
deportation of these decidual proteins. STUDY DESIGN: CA 125 and insulin-like growth …
pregnancy is a fundamental abnormality in preeclampsia. CA 125 and insulin-like growth
factor binding protein-1 are major endometrial proteins whose primary sources are decidual
epithelial and stromal cells, respectively. We hypothesized that reduced trophoblastic
invasion in pregnancies destined for preeclampsia would affect the maternal vascular
deportation of these decidual proteins. STUDY DESIGN: CA 125 and insulin-like growth …
