Reduction of cholera in Bangladeshi villages by simple filtration

RR Colwell, A Huq, MS Islam… - Proceedings of the …, 2003 - National Acad Sciences
RR Colwell, A Huq, MS Islam, KMA Aziz, M Yunus, NH Khan, A Mahmud, RB Sack, GB Nair…
Proceedings of the National Academy of Sciences, 2003National Acad Sciences
Based on results of ecological studies demonstrating that Vibrio cholerae, the etiological
agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple
filtration procedure was developed whereby zooplankton, most phytoplankton, and
particulates> 20 μm were removed from water before use. Effective deployment of this
filtration procedure, from September 1999 through July 2002 in 65 villages of rural
Bangladesh, of which the total population for the entire study comprised≈ 133,000 …
Based on results of ecological studies demonstrating that Vibrio cholerae, the etiological agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple filtration procedure was developed whereby zooplankton, most phytoplankton, and particulates >20 μm were removed from water before use. Effective deployment of this filtration procedure, from September 1999 through July 2002 in 65 villages of rural Bangladesh, of which the total population for the entire study comprised ≈133,000 individuals, yielded a 48% reduction in cholera (P < 0.005) compared with the control.
National Acad Sciences