Coronary C-reactive protein distribution: its relation to development of atherosclerosis

YX Zhang, WJ Cliff, GI Schoefl, G Higgins - Atherosclerosis, 1999 - Elsevier
Two hundred and ninety-nine paraffin-embedded human coronary artery sections from 68
autopsies, both male and female and with various causes of death, were examined for
distribution of C-reactive protein (CRP) using the indirect immunofluorescence technique
and high-resolution confocal microscopy. The results demonstrate, for the first time, the
existence of CRP in human coronary arteries, with evidence of CRP deposits being
associated with lipids within in the artery walls. Grades of CRP immunoreactivity positively …