[CITATION][C] Vascular endothelial growth factor in ocular neovascularization and proliferative diabetic retinopathy
38 MILLER ET AL. induction. In addition, intraocular levels of the the extracellular matrix, 18
but can be released factor should be increased during active intrao-by treatment with high
salt, heparin, heparitincular neovascularization and reduced in times ase or heparinase.
These various observations of quiescence, or following successful treat-have led to the
concept of matrix-associated ment. Finally, inhibition of the factor should bFGF as a “stored
growth factor”. 14 prevent neovascularization. Investigations have strongly implicated bFGF …
but can be released factor should be increased during active intrao-by treatment with high
salt, heparin, heparitincular neovascularization and reduced in times ase or heparinase.
These various observations of quiescence, or following successful treat-have led to the
concept of matrix-associated ment. Finally, inhibition of the factor should bFGF as a “stored
growth factor”. 14 prevent neovascularization. Investigations have strongly implicated bFGF …
38 MILLER ET AL. induction. In addition, intraocular levels of the the extracellular matrix, 18 but can be released factor should be increased during active intrao-by treatment with high salt, heparin, heparitincular neovascularization and reduced in times ase or heparinase. These various observations of quiescence, or following successful treat-have led to the concept of matrix-associated ment. Finally, inhibition of the factor should bFGF as a “stored growth factor”. 14 prevent neovascularization. Investigations have strongly implicated bFGF in angiogenesis. bFGF has been shown to stimulate endothelial cell proliferation and migration, important functions of an angiogenic
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