Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology?
NA Lee, EW Gelfand, JJ Lee - Journal of allergy and clinical immunology, 2001 - Elsevier
Etiologic discussions of allergic respiratory pathology frequently engender rabid
constituencies of pro-T cell or proeosinophil disciples, each claiming, often with religious
fervor, the importance of their leukocyte. However, increasing evidence suggests that the
exclusionary rhetoric from either camp is inadequate to explain many of the pathologic
changes occurring in the lung. Data from both asthmatic patient and mouse models of
allergic respiratory inflammation suggest that, in addition to cell-autonomous activities, T-cell …
constituencies of pro-T cell or proeosinophil disciples, each claiming, often with religious
fervor, the importance of their leukocyte. However, increasing evidence suggests that the
exclusionary rhetoric from either camp is inadequate to explain many of the pathologic
changes occurring in the lung. Data from both asthmatic patient and mouse models of
allergic respiratory inflammation suggest that, in addition to cell-autonomous activities, T-cell …
