Getting to the HAART of T cell dynamics.
M Roederer - 1998 - cabidigitallibrary.org
1998•cabidigitallibrary.org
In this issue of Nature Medicine, reports by Pakker et al.(pp. 208-214) and Gorochov et
al.(pp. 215-221) provide the final nails in the coffin for models of T-cell dynamics in which a
major reason for changes in T-cell numbers is the death of HIV-infected cells. The papers
present extensive data on the remodelling of the T-cell compartment in HIV-infected
individuals after treatment with Highly Active Anti-Retroviral Therapy (HAART, a combination
of 3 antiviral drugs including at least one protease inhibitor).
al.(pp. 215-221) provide the final nails in the coffin for models of T-cell dynamics in which a
major reason for changes in T-cell numbers is the death of HIV-infected cells. The papers
present extensive data on the remodelling of the T-cell compartment in HIV-infected
individuals after treatment with Highly Active Anti-Retroviral Therapy (HAART, a combination
of 3 antiviral drugs including at least one protease inhibitor).
Abstract
In this issue of Nature Medicine, reports by Pakker et al. (pp. 208-214) and Gorochov et al. (pp. 215-221) provide the final nails in the coffin for models of T-cell dynamics in which a major reason for changes in T-cell numbers is the death of HIV-infected cells. The papers present extensive data on the remodelling of the T-cell compartment in HIV-infected individuals after treatment with Highly Active Anti-Retroviral Therapy (HAART, a combination of 3 antiviral drugs including at least one protease inhibitor).
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