[HTML][HTML] Sulfated Lewis X determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin
C Capon, JM Wieruszeski, J Lemoine, JC Byrd… - Journal of Biological …, 1997 - ASBMB
This article describes oligosaccharide structures of mucin isolated from nude mouse
xenograft tumors produced by LS174T-HM7 cells, a subline of the human colon carcinoma
LS174T with higher metastatic tendency and higher mucin production. A striking feature of
the oligosaccharides of the LS174T-HM7 xenograft tumor mucin was a predominance of
sulfated Lewis X determinants: HSO 3-Galβ1–4 (Fucα1–3) GlcNAc. In addition to one
previously known saccharide with one sulfated Lewis X determinant, the HM7 xenograft …
xenograft tumors produced by LS174T-HM7 cells, a subline of the human colon carcinoma
LS174T with higher metastatic tendency and higher mucin production. A striking feature of
the oligosaccharides of the LS174T-HM7 xenograft tumor mucin was a predominance of
sulfated Lewis X determinants: HSO 3-Galβ1–4 (Fucα1–3) GlcNAc. In addition to one
previously known saccharide with one sulfated Lewis X determinant, the HM7 xenograft …