Cell death by apoptosis has fundamental significance in both normal lung homeostasis and
a variety of pathologic processes, and for this reason apoptosis in the lung is a rapidly
growing area of investigation. Evidence from human lung biopsy specimens and from
animal models of lung fibrosis points to important roles for apoptosis in both the
pathogenesis and resolution of fibrotic lesions. As more evidence accumulates, the more
apparent becomes the paucity of information on the regulation of this mode of cell death in …