Prion diseases, blood and the immune system: concerns and reality
A Aguzzi - Haematologica, 2000 - haematologica.org
A Aguzzi
Haematologica, 2000•haematologica.orgThere is a great amount of uncertainty about the nature of the agent which causes
spongiform encephalopathies. In recent years the occurrence of bovine spongiform
encephalopathy and of new variant-Creutzfeldt Jakob disease, has raised concerns that
prions may, under certain circumstances, contaminate the blood supply. This review article
illustrates the problems with which research in this field is fraught, and presents some of the
arguments which are controversially discussed in the field.
spongiform encephalopathies. In recent years the occurrence of bovine spongiform
encephalopathy and of new variant-Creutzfeldt Jakob disease, has raised concerns that
prions may, under certain circumstances, contaminate the blood supply. This review article
illustrates the problems with which research in this field is fraught, and presents some of the
arguments which are controversially discussed in the field.
Abstract
There is a great amount of uncertainty about the nature of the agent which causes spongiform encephalopathies. In recent years the occurrence of bovine spongiform encephalopathy and of new variant-Creutzfeldt Jakob disease, has raised concerns that prions may, under certain circumstances, contaminate the blood supply. This review article illustrates the problems with which research in this field is fraught, and presents some of the arguments which are controversially discussed in the field.
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