Mechanisms regulating adipocyte expression of resistin

HB Hartman, X Hu, KX Tyler, CK Dalal… - Journal of Biological …, 2002 - ASBMB
Resistin, also known as AdipocyteSecreted Factor (ADSF) and Found inInflammatory Zone 3
(FIZZ3), is a mouse protein with potential roles in insulin resistance and adipocyte
differentiation. The resistin gene is expressed almost exclusively in adipocytes. Here we
show that a proximal 264-base pair fragment of the mouse resistin promoter is sufficient for
expression in adipocytes. Ectopic expression of the adipogenic transcription factor
CCAAT/enhancer-binding protein (C/EBPα) was sufficient for expression in non-adipogenic …