Neuropeptides, food intake and body weight regulation: a hypothalamic focus
JJG Hillebrand, D De Wied, RAH Adan - Peptides, 2002 - Elsevier
Energy homeostasis is controlled by a complex neuroendocrine system consisting of
peripheral signals like leptin and central signals, in particular, neuropeptides. Several
neuropeptides with anorexigenic (POMC, CART, and CRH) as well as orexigenic (NPY,
AgRP, and MCH) actions are involved in this complex (partly redundant) controlling system.
Starvation as well as overfeeding lead to changes in expression levels of these
neuropeptides, which act downstream of leptin, resulting in a physiological response. In this …
peripheral signals like leptin and central signals, in particular, neuropeptides. Several
neuropeptides with anorexigenic (POMC, CART, and CRH) as well as orexigenic (NPY,
AgRP, and MCH) actions are involved in this complex (partly redundant) controlling system.
Starvation as well as overfeeding lead to changes in expression levels of these
neuropeptides, which act downstream of leptin, resulting in a physiological response. In this …
