Cow's milk–specific T-cell reactivity of children with and without persistent cow's milk allergy: Key role for IL-10
MM Tiemessen, AG Van Ieperen-Van Dijk… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: The role of antigen-specific T cells in the mechanism of food allergy or
maintenance of tolerance toward an innocuous antigen, such as cow's milk, is not yet fully
understood. OBJECTIVE: The cow's milk–specific T-cell response of donors with various
allergic backgrounds was investigated. METHODS: Cow's milk–specific T-cell clones (TCCs)
were generated from the blood of children with persistent cow's milk allergy (CMA) and the
blood of cow's milk–tolerant allergic and nonallergic control subjects. The TCCs were …
maintenance of tolerance toward an innocuous antigen, such as cow's milk, is not yet fully
understood. OBJECTIVE: The cow's milk–specific T-cell response of donors with various
allergic backgrounds was investigated. METHODS: Cow's milk–specific T-cell clones (TCCs)
were generated from the blood of children with persistent cow's milk allergy (CMA) and the
blood of cow's milk–tolerant allergic and nonallergic control subjects. The TCCs were …