Allergen immunotherapy: therapeutic vaccines for allergic diseases

J Bousquet, R Lockey, HJ Malling… - Annals of allergy …, 1998 - Elsevier
Allergen immunotherapy is the practice of administering gradually increasing quantities of
an allergen extract to an allergic subject to ameliorate the symptoms associated with the
subsequent exposure to the causative allergen. Allergen immunotherapy was introduced to
treat “pollinosis” or allergic rhinitis by Noon and Freeman in 1911. 1 For the past 80 years,
immunotherapy has been used to treat allergic diseases caused by inhalant allergens and
Hymenoptera venoms. Venom immunotherapy is accepted as the standard of care for …