Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study)

C Möller, S Dreborg, HA Ferdousi, S Halken… - Journal of allergy and …, 2002 - Elsevier
Background: Children with allergic rhinitis are likely to develop asthma. Objective: The
purpose of this investigation was to determine whether specific immunotherapy can prevent
the development of asthma and reduce bronchial hyperresponsiveness in children with
seasonal allergic rhinoconjunctivitis. Methods: From 6 pediatric allergy centers, 205 children
aged 6 to 14 years (mean age, 10.7 years) with grass and/or birch pollen allergy but without
any other clinically important allergy were randomized either to receive specific …