[HTML][HTML] N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation
Y Guo, H Wang, Y Okamoto, N Ueda… - Journal of Biological …, 2005 - ASBMB
Implantation requires reciprocal interaction between blastocysts and a receptive uterus. In
mice, one important player in this dialogue involves endocannabinoid signaling via
cannabinoid receptor CB1. Anandamide is an endogenous cannabinoid ligand, and its
levels are spatiotemporally regulated in the uterus during early pregnancy, showing lower
levels in the receptive uterus and at the implantation site. However, the mechanism by which
differential uterine anandamide gradients are established under different pregnancy status …
mice, one important player in this dialogue involves endocannabinoid signaling via
cannabinoid receptor CB1. Anandamide is an endogenous cannabinoid ligand, and its
levels are spatiotemporally regulated in the uterus during early pregnancy, showing lower
levels in the receptive uterus and at the implantation site. However, the mechanism by which
differential uterine anandamide gradients are established under different pregnancy status …