What can the investigation of phosphoinositide signaling system in platelets of schizophrenic patients tell us?
A Strunecka, D Řı́pov - Prostaglandins, leukotrienes and essential fatty …, 1999 - Elsevier
Disturbances in the regulation of the phosphoinositide signaling system have been
proposed as a possible biological marker of schizophrenia. This review considers the
laboratory investigations of phosphoinositide metabolism in platelets of schizophrenic
patients. We suggest that alterations in the inositol phosphate level and a disturbance of
calcium homeostasis may be common denominators for the multiple factors implicated in the
pathogenesis of schizophrenia. In addition, these abnormalities may account for the diverse …
proposed as a possible biological marker of schizophrenia. This review considers the
laboratory investigations of phosphoinositide metabolism in platelets of schizophrenic
patients. We suggest that alterations in the inositol phosphate level and a disturbance of
calcium homeostasis may be common denominators for the multiple factors implicated in the
pathogenesis of schizophrenia. In addition, these abnormalities may account for the diverse …
