[HTML][HTML] Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1, 4, 5-trisphosphate-mediated calcium signaling
LP Haynes, AV Tepikin, RD Burgoyne - Journal of Biological Chemistry, 2004 - ASBMB
Intracellular calcium signals are responsible for initiating a spectrum of physiological
responses. The caldendrins/calcium-binding proteins (CaBPs) represent mammal-specific
members of the CaM superfamily. CaBPs display a restricted pattern of expression in
neuronal/retinal tissues, suggesting a specialized role in Ca 2+ signaling in these cell types.
Recently, it was reported that a splice variant of CaBP1 functionally interacts with inositol 1,
4, 5-trisphosphate (InsP 3) receptors to elicit channel activation in the absence of InsP 3 …
responses. The caldendrins/calcium-binding proteins (CaBPs) represent mammal-specific
members of the CaM superfamily. CaBPs display a restricted pattern of expression in
neuronal/retinal tissues, suggesting a specialized role in Ca 2+ signaling in these cell types.
Recently, it was reported that a splice variant of CaBP1 functionally interacts with inositol 1,
4, 5-trisphosphate (InsP 3) receptors to elicit channel activation in the absence of InsP 3 …
