A double-blinded, randomized, placebo-controlled trial of cetirizine in preventing the onset of asthma in children with atopic dermatitis: 18 months' treatment and 18 …

JO Warner - Journal of Allergy and Clinical Immunology, 2001 - Elsevier
Background: Because asthma is not a curable condition, the development of strategies for
prevention of the disease has a high priority. Atopic dermatitis is a common precursor to the
development of asthma, and 2 studies have suggested that the use of an H1 receptor
antagonist might reduce the development of asthma while the treatment is being
administered, at least in subgroups with evidence of high IgE levels. However, no trial to
date has conducted follow-up after the initial treatment has been stopped to establish …