Expression and localization of histamine H2 receptor messenger RNA in human nasal mucosa
N Hirata, K Takeuchi, K Ukai, C Jin, T Yoshida… - Journal of allergy and …, 1999 - Elsevier
Background: Histamine is an important chemical mediator in allergic rhinitis. Histamine H 2
receptor (H 2 R) stimulation controls histamine release and mediates mucus secretion,
suggesting that H 2 R might play some role in allergic rhinitis. Objective: The objective of this
study was to examine whether H 2 R mRNA expression is increased in patients with allergic
rhinitis compared with normal subjects and to determine the localization of H 2 R mRNA in
the human nasal mucosa. Methods: We extracted RNA from scrapings of the inferior …
receptor (H 2 R) stimulation controls histamine release and mediates mucus secretion,
suggesting that H 2 R might play some role in allergic rhinitis. Objective: The objective of this
study was to examine whether H 2 R mRNA expression is increased in patients with allergic
rhinitis compared with normal subjects and to determine the localization of H 2 R mRNA in
the human nasal mucosa. Methods: We extracted RNA from scrapings of the inferior …
