[43] Cytochrome P-450 arachidonate oxygenase
JH Capdevila, JR Falck, E Dishman, A Karara - Methods in enzymology, 1990 - Elsevier
Publisher Summary The chapter presents a study on cytochrome P-450 arachidonate
oxygenase. Cytochrome P-450, the oxygen-activating component of the microsomal electron
transport system, is an efficient catalyst for the oxygenated metabolism of arachidonic acid
(AA). The chapter mentions that the reaction has an absolute requirement for NADPH and
states the procedure of their stoichiometric relationship. The chapter describes methodology
utilized in laboratory for the biochemical characterization of the hepatic microsomal AA …
oxygenase. Cytochrome P-450, the oxygen-activating component of the microsomal electron
transport system, is an efficient catalyst for the oxygenated metabolism of arachidonic acid
(AA). The chapter mentions that the reaction has an absolute requirement for NADPH and
states the procedure of their stoichiometric relationship. The chapter describes methodology
utilized in laboratory for the biochemical characterization of the hepatic microsomal AA …
