Present status of genetic mechanisms in hypertension

FC Luft - Medical Clinics, 2004 - medical.theclinics.com
Mendelian hypertension is the bright spot in the area of molecular genetics of human
hypertension. The attitude here is that by elucidating rare mendelian diseases, mechanisms
of disease applicable to primary hypertension are understood [1]. This promise has been
kept largely through the efforts and successes of Lifton et al [2]. Through their work,
clinicians have been introduced to numerous disease mechanisms.