[HTML][HTML] Expression of neuronal traits in pancreatic beta cells: implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a …
F Atouf, P Czernichow, R Scharfmann - Journal of Biological Chemistry, 1997 - ASBMB
Pancreatic beta cells (insulin-producing cells) and neuronal cells share a large number of
similarities. Here, we investigate whether the same mechanisms could control the
expression of neuronal genes in both neurons and insulin-producing cells. For that purpose,
we tested the role of the transcriptional repressor neuron-restrictive silencing
factor/repressor element silencing transciption factor (NRSF/REST) in the expression of a
battery of neuronal genes in insulin-producing cells. NRSF/REST is a negative regulator of …
similarities. Here, we investigate whether the same mechanisms could control the
expression of neuronal genes in both neurons and insulin-producing cells. For that purpose,
we tested the role of the transcriptional repressor neuron-restrictive silencing
factor/repressor element silencing transciption factor (NRSF/REST) in the expression of a
battery of neuronal genes in insulin-producing cells. NRSF/REST is a negative regulator of …
