[HTML][HTML] Identification of protein expression signatures associated with Helicobacter pylori infection and gastric adenocarcinoma using recombinant antibody …

P Ellmark, J Ingvarsson, A Carlsson, BS Lundin… - Molecular & Cellular …, 2006 - ASBMB
Antibody microarray based technology is a powerful emerging tool in proteomics, target
discovery, and differential analysis. Here, we report the first study where recombinant
antibody fragments have been used to construct large scale antibody microarrays,
composed of 127 different antibodies against mostly immunoregulatory antigens. The arrays
were based on single framework recombinant antibody fragments (SinFabs) designed for
high on-chip stability and functionality and were used for the analysis of malignant and …