[PDF][PDF] High affinity not in the vicinity?
PA Barker - Neuron, 2007 - cell.com
Neuron, 2007•cell.com
Functional interactions between the p75 neurotrophin receptor (p75NTR) and the Trk
receptors were demonstrated several years ago, but their mechanistic basis remains
uncertain. In this issue of Neuron, Wehrman et al. provide a three-dimensional structure of
the full TrkA ectodomain complexed to NGF and examine the possibility of a ternary p75NTR-
NGF-TrkA complex.
receptors were demonstrated several years ago, but their mechanistic basis remains
uncertain. In this issue of Neuron, Wehrman et al. provide a three-dimensional structure of
the full TrkA ectodomain complexed to NGF and examine the possibility of a ternary p75NTR-
NGF-TrkA complex.
Functional interactions between the p75 neurotrophin receptor (p75NTR) and the Trk receptors were demonstrated several years ago, but their mechanistic basis remains uncertain. In this issue of Neuron, Wehrman et al. provide a three-dimensional structure of the full TrkA ectodomain complexed to NGF and examine the possibility of a ternary p75NTR-NGF-TrkA complex.
cell.com
