The effect of foot-shock on the noxious-evoked activity of neurons in the rostral ventral medulla
MW Friederich, JM Walker - Brain research bulletin, 1990 - Elsevier
The effect of foot-shock on the noxious-evoked activity of rostral ventral medulla (RVM)
neurons was investigated in anesthetized rats. Neurons were first classified as on-cells if
they fired faster during noxious pinch or as off-cells if they fired slower. Exposure to a 20 Hz
squarewave at 2.5 or 3.5 mA administered for two minutes decreased the noxious-evoked
responses of both cell types: on-cells showed a reduced increase in firing, while off-cells
showed a reduced decrease in firing. The results indicate that stress-induced analgesia is …
neurons was investigated in anesthetized rats. Neurons were first classified as on-cells if
they fired faster during noxious pinch or as off-cells if they fired slower. Exposure to a 20 Hz
squarewave at 2.5 or 3.5 mA administered for two minutes decreased the noxious-evoked
responses of both cell types: on-cells showed a reduced increase in firing, while off-cells
showed a reduced decrease in firing. The results indicate that stress-induced analgesia is …
