[CITATION][C] Effect of propranolol in myocardial infarction
PJD Snow - The Lancet, 1965 - Elsevier
Results 93 patients were admitted to the trial (of whom 2 were withdrawn and will be
considered later). Their ages ranged from 31 to 79 years with an average of 59. There were
68 males and 23 females. 45 patients received propranolol and 46 did not. The sex ratio and
age-distribution were similar in both groups. A rough grading of the clinical condition of each
patient was made at the time of admission, and the accompanying table shows the
distribution in the two groups.
considered later). Their ages ranged from 31 to 79 years with an average of 59. There were
68 males and 23 females. 45 patients received propranolol and 46 did not. The sex ratio and
age-distribution were similar in both groups. A rough grading of the clinical condition of each
patient was made at the time of admission, and the accompanying table shows the
distribution in the two groups.
[CITATION][C] Absence of prophylactic effect of propranolol in myocardial infarction
J Clausen, M Felsby, FS Jørgensen, BL Nielsen, J Roin… - The Lancet, 1966 - Elsevier
Summary 114 patients with a confirmed diagnosis of acute myo-cardial infarction took part in
a double-blind, controlled trial of propranolol. The treated group of 56 patients received
propranolol orally, 20 mg. six-hourly for forty-eight days, and the control group of 58 patients
was given placebo tablets. The mortality at twenty-eight days was 23-2% in the treated
group and 24-1% in the control group. There was a significant increase in the development
of sinus bradycardia, and sinus bradycardia with hypo-tension, in the treated group after …
a double-blind, controlled trial of propranolol. The treated group of 56 patients received
propranolol orally, 20 mg. six-hourly for forty-eight days, and the control group of 58 patients
was given placebo tablets. The mortality at twenty-eight days was 23-2% in the treated
group and 24-1% in the control group. There was a significant increase in the development
of sinus bradycardia, and sinus bradycardia with hypo-tension, in the treated group after …
