Thirty-one trabeculectomy specimens of patients suffering from primary open-angle
glaucoma (POAG) who had received no, or only minor, medication prior to surgery were
ultrastructurally and quantitatively analysed. Most of the specimens revealed thickened
trabeculae, increased amounts of plaque-material deposited within the cribriform layer and
an abundance of long spacing (lattice) collagen. The uveal meshwork was partly deprived of
cells whereas the cribriform layer often contained numerous enlarged, light cells with many …