[HTML][HTML] GEC1 interacts with the κ opioid receptor and enhances expression of the receptor

C Chen, JG Li, Y Chen, P Huang, Y Wang… - Journal of Biological …, 2006 - ASBMB
We identified a truncated form (38–117) of GEC1 that interacts with the C-tail of the human κ
opioid receptor (hKOR) by yeast two-hybrid screening. GEC1-(38–117) did not interact with
the C-tail of the μ or δ opioid receptors. GEC1, a 117-amino acid protein (Pellerin, I.,
Vuillermoz, C., Jouvenot, M., Ordener, C., Royez, M., and Adessi, GL (1993) Mol. Cell
Endocrinol. 90, R17–R21), is highly homologous to GABARAP, GATE-16, and Apg8/aut7, all
members of the microtubule associated protein (MAP) family. In pull-down assays, GST …