[HTML][HTML] Behavioral assessment of visual acuity in mice and rats

GT Prusky, PWR West, RM Douglas - Vision research, 2000 - Elsevier
GT Prusky, PWR West, RM Douglas
Vision research, 2000Elsevier
We have developed a simple computer-based discrimination task that enables the quick
determination of visual acuities in rodents. A grating is displayed randomly on one of two
monitors at the wide end of a trapezoidal-shaped tank containing shallow water. Animals are
trained to swim toward the screens, and at a fixed distance, choose the screen displaying
the grating and escape to a submerged platform hidden below it. Both mice and rats learn
the task quickly. Performance falls below 70% when the spatial frequency is increased …
We have developed a simple computer-based discrimination task that enables the quick determination of visual acuities in rodents. A grating is displayed randomly on one of two monitors at the wide end of a trapezoidal-shaped tank containing shallow water. Animals are trained to swim toward the screens, and at a fixed distance, choose the screen displaying the grating and escape to a submerged platform hidden below it. Both mice and rats learn the task quickly. Performance falls below 70% when the spatial frequency is increased beyond 0.5 cycles in most C57BU6 mice, and around 1.0 cycles per degree (cpd) in Long–Evans rats.
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