MULTOVL: fast multiple overlaps of genomic regions

A Aszódi - Bioinformatics, 2012 - academic.oup.com
A Aszódi
Bioinformatics, 2012academic.oup.com
We present the MULTOVL application suite that detects and statistically analyses multiple
overlaps of genomic regions in a fast and efficient manner. The package supports the
detection of multiple region intersections, unions and 'solitary'genomic regions. The
significance of actually observed overlaps is estimated by comparing them with empirical
null distributions generated by random shuffling of the input regions. Availability and
implementation: Source code and binaries are downloadable from: http://www. csf. ac …
Abstract
Summary: We present the MULTOVL application suite that detects and statistically analyses multiple overlaps of genomic regions in a fast and efficient manner. The package supports the detection of multiple region intersections, unions and ‘solitary’ genomic regions. The significance of actually observed overlaps is estimated by comparing them with empirical null distributions generated by random shuffling of the input regions.
Availability and implementation: Source code and binaries are downloadable from: http://www.csf.ac.at/facilities/scc/tools.
Contact:  andras.aszodi@csf.ac.at
Oxford University Press