Rapid activation of the Stat3 transcription complex in liver regeneration
DE Cressman, RH Diamond, R Taub - Hepatology, 1995 - Elsevier
Liver regeneration in response to partial hepatectomy is a physiological growth response
observed in the intact animal. Understanding the early signals that trigger liver regeneration
is of vital importance to understand the liver's response to injury. It has been observed that
several growth factors and cytokines, including epidermal growth factor (EGF) and
interleukin-6 (IL-6), can activate members of the signal transducers and activators of
transcription (Stat) family of transcription factors resulting in tyrosine phosphorylation of …
observed in the intact animal. Understanding the early signals that trigger liver regeneration
is of vital importance to understand the liver's response to injury. It has been observed that
several growth factors and cytokines, including epidermal growth factor (EGF) and
interleukin-6 (IL-6), can activate members of the signal transducers and activators of
transcription (Stat) family of transcription factors resulting in tyrosine phosphorylation of …