Video imaging and spatiotemporal maps to analyze gastrointestinal motility in mice

M Swaminathan, E Hill-Yardin, M Ellis… - JoVE (Journal of …, 2016 - jove.com
The enteric nervous system (ENS) plays an important role in regulating gastrointestinal (GI)
motility and can function independently of the central nervous system. Changes in ENS
function are a major cause of GI symptoms and disease and may contribute to GI symptoms
reported in neuropsychiatric disorders including autism. It is well established that isolated
colon segments generate spontaneous, rhythmic contractions known as Colonic Migrating
Motor Complexes (CMMCs). A procedure to analyze the enteric neural regulation of CMMCs …