Duchenne muscular dystrophy is a severe X-linked hereditary disease caused by the
absence of functional dystrophin. The dystrophin-deficient mdx-mouse strain is a widely
used animal model for dystrophin-deficiency. Several therapeutic approaches for muscular
dystrophy have been proposed by different laboratories. In order to compare the efficacy of
these therapies in the mdx-mouse, it is essential to implement standardized protocols for the
assessment of functional and histological parameters in this mouse model. Here, we …