[PDF][PDF] Muscle development: nucleating microtubules at the nuclear envelope
DA Starr - Current Biology, 2017 - cell.com
Current Biology, 2017•cell.com
Microtubule-organizing centers move from centrosomes to the nuclear envelope during
muscle development. The KASH protein Nesprin-1α recruits pericentriolar material to the
surface of myotube nuclei, where it nucleates microtubules to ensure even spacing of nuclei
within the developing myotube.
muscle development. The KASH protein Nesprin-1α recruits pericentriolar material to the
surface of myotube nuclei, where it nucleates microtubules to ensure even spacing of nuclei
within the developing myotube.
Summary
Microtubule-organizing centers move from centrosomes to the nuclear envelope during muscle development. The KASH protein Nesprin-1α recruits pericentriolar material to the surface of myotube nuclei, where it nucleates microtubules to ensure even spacing of nuclei within the developing myotube.
cell.com
