Characteristic magnetic resonance imaging findings in Machado-Joseph disease
Y Murata, S Yamaguchi, H Kawakami… - Archives of …, 1998 - jamanetwork.com
Objective To clarify the characteristic magnetic resonance imaging (MRI) findings in patients
with Machado-Joseph disease (MJD) diagnosed by genetic analysis. Patients and Methods
Using MRI, we examined 31 patients genetically diagnosed as having MJD, 20 patients with
sporadic olivopontocerebellar atrophy, and 26 control subjects. Results The MRIs of patients
with MJD disclosed remarkably reduced width of the superior cerebellar peduncles, atrophy
in the frontal and temporal lobes, diminished transverse diameter of the globus pallidus, and …
with Machado-Joseph disease (MJD) diagnosed by genetic analysis. Patients and Methods
Using MRI, we examined 31 patients genetically diagnosed as having MJD, 20 patients with
sporadic olivopontocerebellar atrophy, and 26 control subjects. Results The MRIs of patients
with MJD disclosed remarkably reduced width of the superior cerebellar peduncles, atrophy
in the frontal and temporal lobes, diminished transverse diameter of the globus pallidus, and …