CD133 selected stem cells from proliferating infantile hemangioma and establishment of anin vivomice model of hemangioma
H Mai, J Zheng, Y Wang, X Yang, Z Qin… - Chinese medical …, 2013 - journals.lww.com
Background Infantile hemangioma (IH) is the most common benign tumor in children with
prevalence in the face and neck. Various treatment options including oral propranolol have
been described for IH, but the mechanism of drugs remains enigmatic. The aim of this study
was to investigate the pathogenesis and establish a reliable in vivo model of IH which can
provide platform for drug exploration. Methods Stem cells from the proliferating
hemangiomas (HemSCs) were isolated by CD133-tagged immunomagnetic beads. Their …
prevalence in the face and neck. Various treatment options including oral propranolol have
been described for IH, but the mechanism of drugs remains enigmatic. The aim of this study
was to investigate the pathogenesis and establish a reliable in vivo model of IH which can
provide platform for drug exploration. Methods Stem cells from the proliferating
hemangiomas (HemSCs) were isolated by CD133-tagged immunomagnetic beads. Their …
