Heparin’s anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins
Lianchun Wang, … , Ajit Varki, Jeffrey D. Esko
Lianchun Wang, … , Ajit Varki, Jeffrey D. Esko
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):127-136. https://doi.org/10.1172/JCI14996.
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Categories: Article Vascular biology

Heparin’s anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins

Abstract

Research Article

Authors

Lianchun Wang, Jillian R. Brown, Ajit Varki, Jeffrey D. Esko

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Figure 1

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Representative disaccharide units of heparin and the various heparinoids...
Representative disaccharide units of heparin and the various heparinoids. Each disaccharide illustrates a characteristic unit in the indicated preparation and does not represent the overall structure of the chains. X = H or SO3–.